摘要
胆红素是血红素的代谢产物,被认为是一种有害物质,但胆红素具有抗氧化、抗炎、抗动脉粥样硬化等作用。血浆胆红素水平与卒中风险因素呈负相关,对卒中风险有较好的预测作用。胆红素水平与急性脑梗死严重性呈正相关,通过提高体内胆红素水平来预防和治疗心、脑血管疾病尤其是缺血性脑血管病有重要意义。本文就胆红素与脑血管疾病关系的研究进展作一综述。
Bilirubin is a metabolic product of hemocrystallin and has always been thought to be a toxic substance. However, it shows that bilirubin has effects of antioxidant, anti-inflammatory, anti-atherosclerosis, and so on. The serum bilirubin is negatively correlated with the risk factors of stroke, and it could predict the risk for stroke. The serum bilirubin is positively correlated with the severity of acute cerebral infarction, therefore it is important to increase the level of serum bilirubin for preventing and treating cardiovascular and cerebrovascular diseases, especially ischemic cerebrovascular disease. This paper reviews the research progress of the relationship between bilirubin and cerebrovascular disease.
出处
《中华实用诊断与治疗杂志》
2016年第3期209-211,共3页
Journal of Chinese Practical Diagnosis and Therapy
基金
国家自然科学基金(81371273)
关键词
脑梗死
胆红素
脑血管疾病
Cerebral infarction
bilirubin
cerebrovascular disease