期刊文献+

白细胞介素17与血管内皮生长因子在鼻息肉发病中的作用

Research progress of interleukin 17 and vascular endothelial growth factor in the pathogenesis of nasal polyps
原文传递
导出
摘要 鼻息肉是临床鼻科的常见病,其发生是一个多因素、多步骤、多种因子综合参与的复杂的病理生理过程。白细胞介素17是一种强大的前炎症细胞因子,血管内皮生长因子则是已知的最强的血管通透因子,近年来大量研究证实白细胞介素17与血管内皮生长因子在鼻息肉的发生、发展中扮演着重要的角色,且两者之间可能形成一个作用环,共同促进鼻息肉的发生与发展。 Polyp NP (nasal) is a common disease in the clinic. It is a complex pathophysiological process with multiple factors, multiple steps and multiple factors. Interleukin 17 (IL) is a powerful pro-inflammatory cytokine, vascular endothelial growth factor (vascular endothelial growth factor (VEGF) is the strongest known as vascular permeability factor, in recent years a large number of studies have confirmed that IL-17 and VEGF in the occurrence and development of nasal polyps plays an important role and between the two may form a ring, and jointly promote the occurrence and development of nasal polyps.
出处 《国际耳鼻咽喉头颈外科杂志》 2016年第2期92-95,共4页 International Journal of Otolaryngology-Head and Neck Surgery
关键词 白细胞介素17 血管内皮生长因子 鼻息肉 Interleukin 17 Vascular Endothelial Growth Factor Nasal Polyps
  • 相关文献

参考文献11

二级参考文献131

  • 1周艳,徐艳.慢性牙周炎患者基础治疗前后龈沟液中IL-17的表达变化[J].南通大学学报(医学版),2009,29(5):328-330. 被引量:6
  • 2王鑫,董震.鼻息肉组织免疫相关基因的表达谱[J].中华耳鼻咽喉科杂志,2004,39(12):721-724. 被引量:18
  • 3陈金辉,吴建平,陶泽璋,孔勇刚,吴玉珍.36例鼻息肉病的综合治疗及疗效分析[J].临床耳鼻咽喉科杂志,2006,20(8):353-354. 被引量:2
  • 4Seon Hee Chang.A novel heterodimeric cytokine consisting of IL-17 and IL-17F regulates inflammatory responses[J].Cell Research,2007,17(5):435-440. 被引量:48
  • 5Meltzer E O, Hamilos D L, Hadley J A, et al. Rhinosinusitis: establishing defmitions for clinic are search and patient care[J]. JAller Clin Immunol, 2004, 114(6 Suppl) : 156-212.
  • 6Wong C K, Ho C Y, Li E K, et al. Elevation of pro-inflammatory cytokine ( IL-18, IL-17, IL-12) and Th2 cy- tokine(IL-4) concentrations in patients with systemic lu- puserythematosus [J]. Lupus, 2000, 9 (8) :589.
  • 7Molet S M, Hamid Q A, Hamilos D L. IL-11 and IL-17 expression in nasal polyps: relationship to collagen deposition and suppression by intranasal fluticasone propionate [J]. Laryngoscope, 2003, 113(10) :1803-1812.
  • 8Lund V J, Holmstrom M, Scadding G K. Functional endoscopic sinus surgery in the management of chronic rhi- nosisnusitis, An objective assessment [J].J Laryngol Otol, 1991, 105(10) :832-835.
  • 9Zinreich S J. Imaging for staging of rhinosinusit is [ J ]. Ann Otol Rhinol Laryngol , 2004, 193(Suppl) :19-23.
  • 10Lanza D C, Kennedy D W. Adult rhinosinusit is defined [J].Otolaryngol Head Neck Surg, 1997, 117 (3Pt2) : 51- 57.

共引文献61

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部