早期先兆流产中医辨证分型与抗心磷脂抗体阳性的相关性研究

Correlation studies of TCM Syndrome Differentiation and Positive Anticardiolipin Antibody in Early Threatened Abortion

目的:探讨早期先兆流产病中医辨证分型与抗心磷脂抗体(ACA)阳性的相关性,为早期先兆流产的中医辨证分型提供客观化依据,从而指导临床早期先兆流产的中医辨证施治。方法:对168例早期先兆流产病患者进行血清抗心磷脂抗体检测,并依据《中药新药临床研究指导原则》中的标准对每位患者进行中医辨证分型,用SPSS 17.0软件进行统计学分析。结果:早期先兆流产患者肾虚证型和气血虚弱证型ACA阳性率较高,而跌仆损伤证型(血瘀证)次之,血热证型ACA阳性的几率较少。结论:早期先兆流产证型中肾虚证和气血虚弱证与ACA阳性有显著相关性,与跌仆损伤证型(血瘀证)有一定相关性。

Objective： To study the relationship between TCM syndrome differentiation of the early threatened abortion and positive anti cardiolipin antibody（ ACA）,so as to provide an objective basis for TCM syndrome types which can be used to guide the clinical treatment of the early threatened abortion. Methods： Plasma ACA detection of 168 cases of early threatened abortion patients were carried out. According to the standard listed in the Guidance Principle of Clinical Studyon New Drugs of TCM,each patient was conducted TCM syndrome differentiation. The data were analyzed by SPSS17. 0 software. Results： In the early threatened abortion patients with kidney deficiency type and Qi weakness syndrome type the positive rate of the ACA is the highest,the injury syndrome（ blood stasis） takes the second place. The risk of positive ACA blood heat syndrome type is the least. Conclusion： The early threatened abortion syndrome with kidney deficiency and Qi weakness syndrome have significant correlation with positive ACA,and injury syndrome（ blood stasis） has a certain correlation with it.