H型高血压与急性脑梗死的相关性研究

Correlative study between hyperhomocystein-related hypertension and acute cerebral infarction

目的:探讨H型高血压与急性脑梗死(ACI)的相关性。方法:回顾性分析160例高血压患者的临床病历资料,其中H型高血压组90例,单纯高血压组70例,比较2组患者ACI发病率以及TC、TG、HDL-C、LDL-C、Hcy水平,并行多元回归分析这5种因素与ACI的相关性。结果:H型高血压组Hcy水平及ACI发病率均显著高于单纯高血压组(均P<0.05),且H型高血压与ACI的发生具有显著相关性(P<0.05)。结论:H型高血压是ACI最重要的独立危险因素,同时降低血压和Hcy水平的策略可能会降低ACI的发生率。

Objective：To investigate the relationship between H type hypertension and acute cerebral infarction（ACI）.Methods：Clinical data of 160 patients with hypertension were analyzed retrospectively,of which 90 cases were H type hypertension group,and 70 cases were the simple hypertension group.Levels of Hcy,TC,TG,HDL-C,LDL-C and incidence of ACI were compared between the two groups,and multiple regression analysis was used to analyze the correlation between the above factors and ACI.Results：The level of Hey and incidence of ACI in H type hypertension group were higher than those in the simple hypertension group（all P0.05）,and H type hypertension was significantly correlated with the incidence of ACI（P 0.05）.Conclusions：H type hypertension may be an independent risk factor for ACI.The treatment on H type hypertension can reduce the level of Hcy and the incidence of ACI effectively.