聚焦解决模式对2型糖尿病患者血糖影响的Meta分析

Influence of Solution-focused Brief Therapy on Blood Glucose of Patients with Type 2 Diabetes Mellitus:A Meta-analysis

目的评价聚焦解决模式对2型糖尿病患者血糖的影响。方法通过检索Pub Med、Elsevier、Springer、Bio Med、Lancet、FMJS和中国知网、万方数据库、维普资讯、中国生物医学数据库,纳入采用聚焦解决模式应用于2型糖尿病患者的随机对照试验,观察指标包括患者糖化血红蛋白(Hb Alc)、空腹血糖(FPG)和餐后2 h血糖(2 h PG)的对照数据,采用Review Manager 5.3进行Meta分析。结果共纳入8篇随机对照试验,实验组与对照组各516例。聚焦解决模式教育可以明显降低2型糖尿病患者糖化血红蛋白(MD=-0.76,95%CI,-0.86^-0.65,P<0.00001),空腹血糖(MD=-1.16,95%CI,-1.15^-0.78,P<0.00001),餐后2 h血糖数值(MD=-2.10,95%CI,-2.50^-1.71,P<0.00001)。结论与常规传统的说教式教育相比,聚焦解决模式教育可以改善2型糖尿病患者糖化血红蛋白、空腹血糖、餐后2 h血糖水平,但仍需多中心、大样本的临床试验研究来进一步证实此结论。

Objective To evaluate the influence of solution-focused brief therapy on blood glucose in patients with T2DM（type 2diabetes mellitus）.Methods We retrieved Pub Med,Elsevier,Springer,Bio Med,Lancet,FMJS,CNKI,CQVIP,WANGFANG Data,Sino Med to extract the RCTs（randomized controlled trials）on the influence of solution-focused brief therapy on blood glucose of T2 DM patients then Review Manager 5.3 was applied for analysis.Results In eight RCTs included,there were 516 cases in experimental group and control group respectively.Compared with conventional traditional education mode,education mode with solution-focused brief therapy could obviously reduce Hb Alc（MD=-0.76,95%CI,-0.86 to-0.65,P〈0.00001）,FPG（MD=-1.16,95%CI,-1.15 to-0.78,P〈0.00001）,2 HPG（MD =-2.10,95% CI,-2.50 to-1.71,P〈0.00001）of patients with T2 DM.Conclusion Solution-focused brief therapy is effective for improving Hb Alc,FPG and 2HPG of patients with T2 DM,but more clinical experiments with multi-center,large-scale samples are needed.