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妊娠甲状腺功能亢进症对子代脑发育的影响 被引量：3

Influence of pregnancy hyperthyroidism on offspring brain development
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摘要 甲状腺激素是大脑发育期的关键激素。妊娠期甲状腺功能异常可引起脑组织和细胞结构的变化。本文分别从妊娠生理、甲状腺激素作用机制及甲状腺功能亢进症(甲亢)方面阐述了甲状腺激素对胎儿大脑发育的不良影响,并从中得出结论:妊娠期甲亢可能影响胎儿大脑发育,需积极治疗。 Thyroid hormone（TH）is the key to brain development.Thyroid dysfunction during pregnancy can lead to the change of brain tissue and the cell structure.This review illustrates the adverse effect of thyroid hormone on fetal brain development from hyperthyroidism and mechanism of pregnant physiology and thyroid hormone.The conclusion was that hyperthyroidism during pregnancy may affect fetal brain development and needs active treatment.
作者 刘志红 王瑞英
机构地区 河北医科大学第二医院内分泌科
出处 《临床荟萃》 CAS 2016年第3期258-261,共4页 Clinical Focus
基金 河北省科技支撑计划项目(132777132D)
关键词 甲状腺功能亢进症 甲状腺激素类 大脑 妊娠 hyperthyroidism thyroid hormones cerebrum pregnancy
分类号 R581.1 [医药卫生—内分泌]
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参考文献25

  • 1单忠艳.妊娠合并甲状腺功能减退症的进展和争论[J].内科理论与实践,2010,5(2):125-129. 被引量：75
  • 2Chan GW, Mandel SJ. Therapy insight: management of Graves' disease during pregnaney [J]. Nat Clin Pract Endocrinol Metab,2007, 3(6): 470-478.
  • 3Haddow JE, MeClain MR, Lambert-Messerlian O, et al. Variability in thyroid-stimulating hormone suppression by human chorionic [ corrected ] gonadotropin during early pregnancy[J]. J Clin Endocrinol Metab, 2008, 93(9): 3341- 3347.
  • 4Gaberscek S, Zaletel K, et al. Thyroid physiology and autoimmunity in pregnancy and after delivery [ J ]. Clin Immunol, 2011, 7(5): 697-706.
  • 5Fister P, Gaberscek S, Zaletel K, et al. Thyroid volume changes during pregnancy and after delivery in an iodine- sufficient Republic of Slovenia [J]. Eur J Ohstet Gynecol Reprod Biol,2009, 145(1) : 45-48.
  • 6Chan SY, Vasilopoul.ou E, Kilby MD. The role of the placenta in thyroid hormone delivery to the fetus[J].Nat Clin Pract Endocrinol Metab, 2009,5 (1) 45-54.
  • 7Wallis K, Dudazy S, Van Hogeriinden M, et al. The thyroid hormone receptor alphal protein is expressed in embryonic postmitotic neurons and persists in most adult neurons[J]. Mol Endocrinol, 2010,24 (10) 1904-1916.
  • 8Calzd L,Ferndndez M,Giardino L. Role of the thyroid system in myelination and neural connectivity [J]. Compr Physiol, 2015, 5(3) :1405-1421.
  • 9Calz[J]. L,Fernandez M,Giardino L. Role of the thyroid system in myelination and neural connectivity [J]. Compr Physiol, 2015, 5(3) :1405-1421.
  • 10Bhumika S, Darras VM. Role of thyroid hormones in different aspects of nervous system regeneration in vertebrates[J].Gen Comp Endocrinoi, 2014,203 : 86-94.

二级参考文献36

  • 1朱德发,谭忠林,庄骏,周江宁.亚临床型甲状腺功能减退症对老年人认知功能的影响[J].中国临床保健杂志,2004,7(5):343-344. 被引量：11
  • 2李兰英,刘春蓉,石峰,臧晓怡,刘亚敏,孙云,阚伯红.甲亢大鼠脑甲状腺激素受体mRNA的表达[J].天津医药,2006,34(12):877-879. 被引量：1
  • 3Panesar NS,Li CY,Rogers MS.Reference intervals for thyroid hormones in pregnant Chinese women[J].Ann Clin Biochem,200l,38 Pt 4:329-332.
  • 4Abalovich M,Amino N,Barbour LA,et al.Management of thyroid dysfunction during pregnancy and postpartum:an Endocrine Society Clinical Practice Guideline[J].J Clin Endocrinol Metab,2007,92(8 Suppl):S1-S47.
  • 5Pop VJ,Brouwers EP,Vader HL,et al.Maternal hypothyroxinaemia during early pregnancy and subsequent child development:a 3-year follow-up study[J].Clin Endocrinol(Oxf),2003,59(3):282-288.
  • 6Stricker R,Echenard M,Eberhart R,et al.Evaluation of maternal thyroid function during pregnancy:the importance of using gestational age-specific reference intervals[J].Eur J Endocrinol,2007,157(4):509-514.
  • 7Shan ZY,Chen YY,Teng WP,et al.A study for maternal thyroid hormone deficiency during the first half of pregnancy in China[J].Eur J Clin Invest,2009,39(1):37-42.
  • 8Casey BM,Dashe JS,Wells CE,et al.Subclinical hypothyroidism and pregnancy outcomes[J].Obstet Gynecol,2005,105(2):239-245.
  • 9Allan WC,Haddow JE,Palomaki GE,et al.Maternal thyroid deficiency and pregnancy complications:implications for population screening[J].J Med Screen,2000,7(3):127-130.
  • 10Cleary-Goldman J,Malone FD,Lambert-Messedian G,et al.Maternal thyroid hypofunction and pregnancy outcome[J].Obstet Gynecol,2008,112(1):85-92.

共引文献79

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临床荟萃
2016年 第3期

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