摘要
目的探讨年龄相关性血管硬度与血压的关系。方法选取2014年6月—2015年6月在天津市西青医院进行健康体检者504例,根据年龄分为青年组(≤44岁,n=82)、中年组(45-59岁,n=230例)、老年组(60-79岁,n=135例)和高龄组(≥80岁,n=57)。比较各组受试者血压及血管硬度,并分析血管硬度与血压的关系。结果青年组高血压检出率为20.73%(17/82),中年组为32.61%(75/230),老年组为42.22%(57/135),高龄组为43.86%(25/57)。高龄组、老年组和中年组受试者收缩压和脉压高于青年组,高龄组和老年组受试者收缩压和脉压高于中年组(P〈0.05);但老年组和高龄组受试者收缩压和脉压比较,差异无统计学意义(P〉0.05);各组受试者舒张压比较,差异无统计学意义(P〉0.05)。高龄组、老年组和中年组受试者左侧踝臂脉搏波传导速度(baPWV)和右侧baPWV均高于青年组,高龄组和老年组受试者左侧baPWV和右侧baPWV均高于中年组,高龄组受试者左侧baPWV和右侧baPWV均高于老年组(P〈0.01);高龄组、老年组和中年组受试者左侧踝臂指数(ABI)和右侧ABI均高于青年组,高龄组受试者左侧ABI高于中年组、老年组(P〈0.01)。Pearson相关性分析结果显示,年龄与左侧baPWV和右侧baPWV均呈正相关(r值分别为0.531、0.556,P〈0.01);而年龄与左侧ABI和右侧ABI均无直线相关性(r值分别为0.137、0.004,P〉0.05)。Mantel-Haenszel卡方检验结果显示,右侧baPWV与高血压分级无关(χ^2=1 229.67,P=0.355),左侧baPWV与高血压分级亦无关(χ^2=1 239.35,P=0.277);右侧ABI(χ^2=419.81)和左侧ABI(χ^2=351.59)均与高血压分级有关(P〈0.001)。结论随着年龄增长,血管硬度增加、收缩压升高,且血管硬度与血压有关。
Objective To investigate the relationship between age- related vascular hardness and blood pressure.Methods From June 2014 to June 2015, a total of 504 cases admitted to Xiqing Hospital for physical examination were collected,and they were divided into A group( below or equal 44 years old,n = 82),B group( between 45 and 59 years old,n = 230),C group( between 60 and 79 years old,n = 135) and D group( equal or over 80 years old,n = 57) according to age. Blood pressure and vascular hardness were compared among the four groups,and relationship between vascular hardness and blood pressure was analyzed. Results The detection rate of hypertension of A group was 20. 73%( 17 /82),of B group was32. 61%( 75 /230),of C group was 42. 22%( 57 /135),of D group was 43. 86%( 25 /57). SBP and pulse pressure of B group,C group and D group were statistically significantly higher than those of A group,SBP and pulse pressure of C group and D group were statistically significantly higher than those of B group( P〈0. 05); while no statistically significant differences of SBP or pulse pressure was found between C group and D group,nor was DBP among the four groups( P〉0. 05). Left- side baPWV and right- side baPWV of B group,C group and D group were statistically significantly higher than those of A group,left- side baPWV and right- side baPWV of C group and D group were statistically significantly higher than those of B group,left- side baPWV and right- side baPWV of D group were statistically significantly higher than those of C group( P〈0. 01). Left- side ABI and right- side ABI of B group,C group and D group were statistically significantly higher than those of A group,left- side ABI and right- side ABI of D group were statistically significantly higher than those of B group and C group( P〈0. 01). Pearson correlation analysis showed that,age was positively correlated with left- side baPWV( r = 0. 531,P〈0. 01)and right- side baPWV( r = 0. 556,P〈0. 01),while age was not linearly correlated with left- side ABI( r = 0. 137,P〉0. 05) or right- side ABI( r = 0. 004, P〉0. 05). Mantel- Haenszel chi- square test results showed that, right- side baPWV( χ^2= 1 229. 67,P = 0. 355) or left- side baPWV( χ^2= 1 239. 35,P = 0. 277) was not correlated with hypertension grading,while right- side ABI( χ^2= 419. 81) and left- side ABI( χ^2= 351. 59) were correlated with hypertension grading( P 0. 001). Conclusion As the increasing of age,the vascular hardness and SBP elevated,and vascular hardness has certain correlation with blood pressure.
出处
《实用心脑肺血管病杂志》
2016年第2期32-35,共4页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
血管硬化
年龄因素
血压
踝臂脉搏波传导速度
踝臂指数
Vascular stiffness
Age factors
Blood pressure
Ankle brachial pulse wave velocity
Ankle brachial index