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茶多酚漱口液对牙周炎患者脂联素及炎症因子的影响 被引量:9

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摘要 目的探讨茶多酚漱口液干预对牙周炎患者脂联素及炎症因子变化的影响。方法纳入我院2010年6月至2014年9月口腔内科牙周炎患者156例,分成3组,茶多酚含漱液组48例,洗必泰含漱液组62例和空白含漱液组46例,设30例健康成年人为正常对照组。分别于基线水平和各组治疗3个月后观察受试者的临床指标,包括牙周探诊深度(PD)、附着丧失(AL)、出血指数(BI)、菌斑指数(PLI)、探诊后出血以及脂联素和炎症因子水平。结果治疗3个月后,空白含漱液组与治疗前相比差异无统计学意义(P>0.05);洗必泰含漱液组与治疗前相比差异有统计学意义(P<0.05);茶多酚漱口液组治疗3个月后的疗效明显优于治疗前及洗必泰含漱液组(P<0.05);茶多酚含漱液组和洗必泰含漱液组治疗3个月后脂联素水平较治疗前上升(P<0.05),而炎症因子C反应蛋白、肿瘤坏死因子-α、白细胞介素-6较治疗前下降,且茶多酚漱口液组治疗后脂联素水平较其他组明显上升,炎症因子较其他两组明显下降,差异有统计学意义(P<0.05),而与正常对照组比较差异无统计学意义(P>0.05)。结论茶多酚漱口液可以改善牙周炎患者的脂联素以及炎症因子水平,有利于牙周炎的炎症控制。
出处 《广东医学》 CAS 北大核心 2016年第4期613-615,共3页 Guangdong Medical Journal
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参考文献15

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