摘要
目的:调查广州地区女性性工作者(FSWs)梅毒感染率及危险因素,指导针对该人群的梅毒防治工作。方法:采用方便抽样法,知情同意后填写结构式问卷,并采集2 m L静脉血分离血清,TRUST、TPPA分别检测梅毒非特异性、特异性抗体,结果和问卷资料用SPSS 13.0分析。结果:共调查FSWs279名,血清TPPA阳性率为8.2%,梅毒感染率为1.43%。按照服务场所分类,中低档场所服务FSWs的血清TPPA阳性率为9.4%,梅毒感染率为1.64%;高档场所FSWs梅毒血清阳性率及感染率为0。多因素分析发现婚姻状态单身者(OR=14.85,95%CI 1.69-130.71)、既往有非梅毒STD史(OR=19.54,95%CI 4.21-90.61)是危险因素。结论:广州地区FSWs梅毒血清阳性率比国内其他城市略低,且主要是中低档FSWs为主,结合其特点开展针对该人群的梅毒防治工作非常必要。
Objective: To investigate syphilis prevalence and risk factors for female sex workers( FSWs) in Guangzhou. Methods: Female sexual workers( FSWs) who agreed to participate in the study were interviewed with a brief questionnaire and were provided free serum syphilis antibody screening with TRUST and TPPA. Data was analyzed by SPSS 13. 0. Results: Of 279 FSWs included,23 were TPPA positive accounting for 8. 2%,and the seroprevalence rate of both TRUST and TPPA was 1. 43%. Analyzing according to venues category,seroprevalence rate for FSWs working in mid-to-low tier was 9. 4%,and the incidence of syphilis was 1. 64%; none of FSWs working in high tier was seropositive syphilis. Multivariate regression analysis showed both single marital status( OR = 14. 85,95% CI 1. 69 - 130. 71) and STD history( OR = 19. 54,95% CI4. 21 - 90. 61) were still risk factors for FSW syphilis. Conclusion: The mobidity of syphilis among FSWs in Guangzhou is slightly lower than that in other province of China,and mainly occurred in mid-to-low tier. It is necessary to integrate the characteristic of the infection in order to carry out intervention to prevent syphilis among FSWs in Guangzhou.
出处
《皮肤性病诊疗学杂志》
2016年第1期52-56,共5页
Journal of Diagnosis and Therapy on Dermato-venereology
基金
广州市科技攻关项目(编号:201300000166)
广州市医药卫生科技重大项目(编号:20121A031001)
关键词
梅毒
女性性工作者
流行
干预
因素
Syphilis
Female sex worker
Prevalence
Intervention
Factors