广州地区女性性工作者梅毒感染率及影响因素分析

Analysis on Syphilis Mobidity and Influence Factors among Female Sex Workers in Guangzhou

目的：调查广州地区女性性工作者（FSWs）梅毒感染率及危险因素,指导针对该人群的梅毒防治工作。方法：采用方便抽样法,知情同意后填写结构式问卷,并采集2 m L静脉血分离血清,TRUST、TPPA分别检测梅毒非特异性、特异性抗体,结果和问卷资料用SPSS 13.0分析。结果：共调查FSWs279名,血清TPPA阳性率为8.2%,梅毒感染率为1.43%。按照服务场所分类,中低档场所服务FSWs的血清TPPA阳性率为9.4%,梅毒感染率为1.64%;高档场所FSWs梅毒血清阳性率及感染率为0。多因素分析发现婚姻状态单身者（OR=14.85,95%CI 1.69-130.71）、既往有非梅毒STD史（OR=19.54,95%CI 4.21-90.61）是危险因素。结论：广州地区FSWs梅毒血清阳性率比国内其他城市略低,且主要是中低档FSWs为主,结合其特点开展针对该人群的梅毒防治工作非常必要。

Objective： To investigate syphilis prevalence and risk factors for female sex workers（ FSWs） in Guangzhou. Methods： Female sexual workers（ FSWs） who agreed to participate in the study were interviewed with a brief questionnaire and were provided free serum syphilis antibody screening with TRUST and TPPA. Data was analyzed by SPSS 13. 0. Results： Of 279 FSWs included,23 were TPPA positive accounting for 8. 2%,and the seroprevalence rate of both TRUST and TPPA was 1. 43%. Analyzing according to venues category,seroprevalence rate for FSWs working in mid-to-low tier was 9. 4%,and the incidence of syphilis was 1. 64%; none of FSWs working in high tier was seropositive syphilis. Multivariate regression analysis showed both single marital status（ OR = 14. 85,95% CI 1. 69 - 130. 71） and STD history（ OR = 19. 54,95% CI4. 21 - 90. 61） were still risk factors for FSW syphilis. Conclusion： The mobidity of syphilis among FSWs in Guangzhou is slightly lower than that in other province of China,and mainly occurred in mid-to-low tier. It is necessary to integrate the characteristic of the infection in order to carry out intervention to prevent syphilis among FSWs in Guangzhou.