摘要
目的研究猫须草[Clerodendranthus spicatus(Thunb.)C.Y.Wu]中的酚酸类化学成分。方法采用大孔树脂柱色谱、凝胶柱色谱及高效液相色谱等方法进行分离纯化,根据理化性质及波谱数据对化合物的结构进行鉴定。结果从猫须草水提取物中得到1个具有新颖桥环[2.2.2]的酚酸类化合物1。结论化合物1为新化合物,命名为猫须草酸E。
OBJECTIVE To study the phenolic acids from the aerial part of Clerodendranthus spicatus. METHODS The phenolic acids were isolated from the aqueous extract of C. spicatus by various chromatographic methods, and their structures were elucidated on the basis of their physicochemistry properties and spectral data. RSULTS A new phenolic acid possess a unique bicycle [ 2. 2. 2 ] octane skeleton was obtained from the aqueous extract of the aerial part of C. spicatus. CONCLUSION Compound 1 is a new phenolic acid and named eleroden E.
出处
《中国药学杂志》
CAS
CSCD
北大核心
2016年第5期365-367,共3页
Chinese Pharmaceutical Journal
基金
国家十二五“重大新药创制”创新药物研究开发技术平台建设资助项目(2012ZX09301-002-001)
关键词
唇形科
肾茶属
猫须草
酚酸类化合物
猫须草酸E
Lamiaceae
Clerodendranthus
Clerodendranthus spicatus
phenolic acid, cleroden E
