腔内超声引导细针穿刺异位妊娠囊注射甲氨蝶呤治疗宫外孕的临床分析

Clinical Analysis of Methotrexate Injection by Ectopic Gestational Sac Puncture Via Fine-needle under Intracavitary Ultrasound Guidance in the Treatment of Ectopic Pregnancy

目的探讨腔内超声引导细针穿刺异位妊娠囊注射甲氨蝶呤治疗宫外孕临床疗效。方法 66例宫外孕患者,按照随机数字法分为实验组和对照组,各33例。对照组予以常规的静脉滴注甲氨蝶呤治疗,实验组则予以腔内超声引导细针穿刺异位妊娠囊注射甲氨蝶呤治疗。结果实验组患者治疗4 d后、7 d后血清β-HCG水平为均显著优于对照组(P<0.05);并且实验组患者的β-HCG转阴时间显著低于对照组(P<0.05)。实验组总有效率为显著高于对照组(P<0.05)。结论腔内超声引导细针穿刺异位妊娠囊注射甲氨蝶呤治疗宫外孕能提高临床疗效,是一种安全、有效的治疗方式。

Objective To explore the clinical effect of methotrexate injection by ectopic gestational sac puncture via fine-needle under intracavitary ultrasound guidance in the treatment of ectopic pregnancy. Methods 66 cases of ectopic pregnancy patients were randomly divided into study group and control group with 33 cases each. Control group was given regular methotrexate IV treatment, study group was given methotrexate injection by ectopic gestational sac puncture via fine-needle under intracavitary ultrasound guidance. Results The serum β-HCG levels of 4 days, 7 days after treatment of study group were significantly better than control group（P〈0.05）; the total effective rate of study group was significantly higher than control group. Conclusion Methotrexate injection with intracavitary ultrasound guided fine needle aspiration ectopic pregnancy sac can improve the clinical efficacy, and it is a safe and effective treatment.