肛周脓肿切排术后联合抗生素与中药的临床比较

Clinical comparison between antibiotic and TCM medicine following perianal abscess surgery

目的:探讨肛周脓肿切排术后联合抗生素与中药的临床疗效及预后影响差异。方法:选取113例肛周脓肿切排术患者为研究对象,根据其治疗意愿分成抗生素组(A组,n=50)和中药组(B组,n=63)。A组采用口服替硝唑片联合高锰酸钾液稀释坐浴方案治疗,B组采用消痈饮内服联合五味消毒饮坐浴方案治疗。对比两组患者临床治疗效果、复发率及相关不良反应发生情况,记录其感染控制时间、创口愈合时间、总住院时间等治疗指标差异。结果:1两组患者在感染控制时间、创口愈合时间及总住院时间等指标的对比上无统计学意义(P>0.05);2两组患者在治疗效果对比上无明显差异(P>0.05);A组不良反应发生率为26.0%,复发率为18.0%,明显高于B组的1.6%和1.6%(P<0.05)。结论:对肛周脓肿患者予以切排术联合中药治疗方案疗效确切,值得临床推广。

Objective： To evaluate prognostic differences of TCM mediicine and antibiotic following the perianal abscess operation. Methods： 113 patients were divided into the antibiotic treatment group（group A, n = 50） and TCM group（group B, n = 63）. Group A took oral tinidazole tablets plus diluted potassium permanganate solution bath solutions; group B took oral Xiaoyong Yin plus Wuwei Xiaodu Yin bath solution. Results： 1 In two groups, the time of infection control, wound healing showed no statistically significant difference between（P 0.05）; 2 clinical efficacy were not significantly different（P0.05） in the two groups; adverse reactions was 26.0% in group A; the recurrence rate was 18.0%, significantly higher than 1.6% and 1.6% in group B（P0.05）. Conclusions： Patients with perianal abscess surgery should take TCM therapy, with better adverse reaction and recurrence controlling.