茵栀黄颗粒和蒙脱石散联合治疗新生儿病理性黄疸的临床效果

Clinical efficacy of the Yinzhihuang granules plus Montmorillonite on pathologic jaundice in newborn infants

目的:探讨对新生儿病理性黄疸采用茵栀黄颗粒联合蒙脱石散治疗的临床效果。方法:随机选取我院于2013年1月-2015年1月收治的80例新生儿病理性黄疸患儿,分为联合组与对照组,各40例,对照组采用蒙脱石散治疗,联合组在应用蒙脱石散的基础上联合茵栀黄颗粒治疗。结果:联合组的总有效率为97.50%,显著高于对照组的77.50%,差异有统计学意义(P<0.05);联合组治疗后的总胆红素水平显著低于对照组,且黄疸消退时间显著短于对照组,差异有统计学意义(P<0.05)。结论:茵栀黄颗粒联合蒙脱石散能快速、有效地降低患儿总胆红素水平及促进黄疸的消退,值得推广。

Objective To explore clinical efficacy of the Yinzhihuang granules plus Montmorillonite on pathologic jaundicein newborn infants. Methods： 80 cases in our hospital from January 2013 to January 2015 were divided into the combined group andthe control group, 40 cases in each group. The control group was given Montmorillonite, and the combined group was treated withYinzhihuang granules plus Montmorillonite. Results： The total efficiency in combined group was 97.50%, and higher than 77.50% in thecontrol group. There was a statistically significant difference （P〈0.05）. The total bilirubin levels after treatment in the combined groupwas significantly lower. And the disappeared time of jaundice was significantly shorter （P〈0.05）. Conclusion： The Yinzhihuang granulesplus Montmorillonite can quickly and effectively reduce the total bilirubin level and promote regression of pathologic jaundice of children,should be promoted.