可移植人体外耳支架的3D打印关键技术

Key technology of transplantable human auricular scaffold based on 3D printing

探索使用医用硅胶制作患者个体外耳支架的关键技术,使用计算机断层扫描和逆向建模技术得到对应患者个体的外耳数字模型,利用3D打印技术制造人体外耳支架模具,并使用医用硅胶MED 4735完成人体外耳支架的制作成型。动物实验验证了其生物相容性,证明了方法的可行性。通过该技术制作的硅胶人体外耳支架可以高度模仿患者特定的耳廓形状,支架精度高、制造周期短、无生物排异,可为替代肋软骨雕刻人体外耳支架进行耳廓缺损治疗提供依据。

The key technology of making human auricular scaffold by using medical silicon was researched. CT scan and reversed modeling were used to obtain the digital auricular model. And the 3D printing technology was utilized to manufacture the mold of auricular scaffold. The medical silicon MED 4735 was used as the material of the scaffold. Animal experiments were then implemented to examine the biocompatibility of the scaffold. The scaffold made by these technologies highly imitates a normal auricle,with high accuracy,short manufacturing cycle,and no immune rejection,which provides the basis for further clinical human experiments.