摘要
白细胞介素-22(IL-22)作为肝细胞癌(HCC)患者体内兼具保护性作用和促进炎症应答双重功能的细胞因子,以多样化的角色参与疾病的发生和发展。近年来对于IL-22在HCC中的研究越来越多,但其在HCC中所发挥的作用仍存在一定争议。本文主要对IL-22的生物学特性及其在HCC发生、发展过程及治疗的作用作一综述。
Interleukin - 22 ( IL - 22), as the dual functions of cytokines, plays diverse roles in disease occur- rence and development in the hepatocellular carcinoma (I-ICC) patients. For IL - 22 in recent years more and more re- search in HCC, but its role in HCC remains controversial. In this paper, it pay attention to the biological characteris- tics of IL - 22 and its role in HCC occurrence, development process and the treatment. IL - 22, as the dual functions of cytokines, plays diverse roles in disease occurrence and development in the HCC patients. For IL - 22 in recent years more and more research in HCC, but its role in I-ICC remains controversial. In this paper, it pay attention to the biological characteristics of IL -22 and its role in HCC occurrence, development process and the treatment.
出处
《中华实验外科杂志》
CAS
CSCD
北大核心
2016年第3期845-847,共3页
Chinese Journal of Experimental Surgery
基金
基金项目:国家自然科学基金(81072152)
湖北省自然科学基金(2015CFA027)
湖北省卫生计划生育委员会科研基金(WJ2015MA010)
关键词
白细胞介素-22
肝细胞癌
免疫
肿瘤
Interleukin - 22
Hepatocellular carcinoma
Immunity
Oncology