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The neuroprotective effects of the anti-diabetic drug linagliptin against Aβ-induced neurotoxicity 被引量:2

The neuroprotective effects of the anti-diabetic drug linagliptin against Aβ-induced neurotoxicity
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摘要 Impaired insulin signaling in Alzheimer’s disease(AD)brains:The insulin signaling pathway is a fundamental physiological mechanism that presents in nearly all vertebrate cells.However,sometimes cells stop responding properly to insulin stimulation.This condition is known as insulin resistance,which is a hallmark of two very common conditions,metabolic syndrome and type 2 diabetes(T2D). Impaired insulin signaling in Alzheimer’s disease(AD)brains:The insulin signaling pathway is a fundamental physiological mechanism that presents in nearly all vertebrate cells.However,sometimes cells stop responding properly to insulin stimulation.This condition is known as insulin resistance,which is a hallmark of two very common conditions,metabolic syndrome and type 2 diabetes(T2D).
机构地区 Institute of Medicine
出处 《Neural Regeneration Research》 SCIE CAS CSCD 2016年第2期236-237,共2页 中国神经再生研究(英文版)
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