脑梗死患者医院感染病原菌耐药性分析

Drug resistance of pathogens causing nosocomial infections in patients with cerebral infarction

目的探讨脑梗死患者医院感染病原菌及耐药性,总结预防医院感染的对策。方法选择2014年2月-2015年2月医院收治的120例脑梗死并发医院感染患者,对患者的痰液、血液以及尿液等标本进行细菌培养,分析病原菌的构成与感染部位,数据采用SPSS 16.0软件进行统计分析。结果 120例患者中以下呼吸道感染为主,共48例占40.0%;共分离出200株病原菌,以革兰阴性菌为主,共136株占68.0%;肺炎克雷伯菌、铜绿假单胞菌、鲍氏不动杆菌、金黄色葡萄球菌对亚胺培南、美罗培南、万古霉素敏感,敏感率为100.0%。结论对脑梗死并发医院感染患者合理使用抗菌药物,并采取有效预防对策,能够有效降低医院感染率。

OBJECTIVE To explore the distribution and drug resistance of pathogens causing nosocomial infections in patients with cerebral infarction and put forward the prevention countermeasures for the nosocomial infections.METHODS A total of 120 cerebral infarction patients complicated with nosocomial infections who were treated in the hospital from Feb 2014 to Feb 2015 were enrolled in the study,then the sputum,blood,and urine specimens were collected for the bacterial culture,the constituent ratios of the pathogens and the infection sites were observed,and the statistical analysis of data was performed with the use of SPSS 16.0software.RESULTS Of the120 patients with nosocomial infections,48（40.0%）had lower respiratory tract infections.Totally 200 strains of pathogens were isolated,of which 68.0%（136strains）were gram-negative bacteria.The drug susceptibility rates of the Klebsiella pneumoniae,Pseudomonas aeruginosa,Acinetobacter baumannii,and Staphylococcus aureus to imipenem,meropenem,and vancomycin were 100.0%.CONCLUSIONIt is an effective way to reasonably use antibiotics for the cerebral infarction patients complicated with nosocomial infections and take the effective prevention countermeasures so as to reduce the incidence of nosocomial infections.