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生物信息学在蛋白质(酶)改造及设计中应用的新进展 被引量：2

Research Progress of Molecular Modification and Design of Novel Proteins(Enzymes) Based on Bioinformatics
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摘要 蛋白质(酶)的改造和设计是人类面对纷繁复杂自然界的一个重大挑战,是自然进化的突发事件,是人类不断掌握自然规律的必然结果,对人类更深入地了解蛋白质结构与功能,促进生物蛋白工业生产具有重大的意义。本文介绍了新型蛋白质(酶)改造和设计的新思路和实施过程,以及目前生物酶改造和设计的一些前沿研究团队和研究成果,以期为生物酶或蛋白质的改造与设计提供借鉴。 The molecular modification and design of proteins（ enzymes） are major challenges for human beings in the face of complex nature. They happened in accident incidents and adhered to inevitable law in the natural evolution of proteins,which is meaningful for the protein industry. In this paper,new strategies and the implementation process for the molecular modification and design of novel biological enzymes are introduced,as well as some advanced research teams and their achievements,in order to provide reference for proteins molecular modification and design.
作者 孙伟峰 钟文娟 孙彬 伍圆明 苟赟 林泉秀 陈祥贵 刘义
机构地区 西华大学食品与生物工程学院食品生物技术四川省高校重点实验室
出处 《西华大学学报（自然科学版）》 CAS 2016年第2期67-71,共5页 Journal of Xihua University:Natural Science Edition
基金 国家自然科学基金(21506172) 四川省教育厅项目(15205445) 西华大学校重点项目(z1420524) 西华大学校重点项目(z1420525) 西华大学食品生物技术重点实验室项目(szjj2015-013 szjj2015-014) 大学生创新创业训练计划(201510623003 201510623053)
关键词 生物信息学 蛋白质改造 酶设计 bioinformatics proteins molecular modification enzymes design
分类号 Q816 [生物学—生物工程]
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参考文献28

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西华大学学报（自然科学版）
2016年 第2期

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