皮肤创面诱导凝胶在小儿包茎术后的临床应用

Benefit of post-circumcision application of skin wound induction gel in the treatment of phimosis in children

目的：探讨皮肤创面诱导凝胶对小儿包茎术后阴茎头结痂率、刀口甲级愈合率及愈合时间的影响。方法：选取行包皮环切术的小儿包茎患者48例,年龄均在6～13岁,随机分为两组,试验组25例,术后应用皮肤创面诱导凝胶涂抹于阴茎头及刀口缝合处,对照组23例,术后应用常规的碘伏棉球消毒,观察并比较两组患者阴茎头结痂率、刀口甲级愈合率、愈合时间。结果：试验组阴茎头结痂3例,对照组17例,差异有统计学意义（12.0%vs 73.9%,P〈0.01）。两组患儿的刀口甲级愈合率无明显差异。试验组愈合时间较对照组短,差异有统计学意义[（10.7±1.7）d vs（11.9±2.1）d,P〈0.05]。结论：小儿包茎术后常规应用皮肤创面诱导凝胶进行术区护理,能有效减少阴茎头分泌物、减轻刀口炎症反应及缩短愈合时间,有较好的临床应用价值。

Objective： To study the effects of skin wound induction gel on the glans scabbing rate,class-A wound healing rate,and wound healing time of circumcision for phimosis in pediatric patients. Methods： We randomly assigned 48 six to thirteen years old children with phimosis to an experimental group（ n = 25） and a control group（ n = 23） to be treated by circumcision. After surgery,the patients in the experimental group received application of skin wound induction gel while those in the control group received that of povidone iodine only to the glans and incision. We recorded and compared the glans scabbing rate,class-A wound healing rate,and wound healing time between the two groups of patients. Results： Glans scabbing was observed in 3 cases in the experimental group and 17 cases in the control group（ 12. 0% vs 73. 9%,P〈0. 01）. No statistically significant differences were found in the rate of class-A wound healing between the two groups（ 100% vs 91. 3%,P〉0. 05）. The wound healing time was significantly shorter in the experimental than in the control group（ [10. 7 ± 1. 7]d vs [11. 9 ± 2. 1]d,P〈0. 05）. Conclusion： Post-circumcision application of skin wound induction gel to the glans and incision can effectively reduce glans secreta,alleviate inflammatory reaction,and shorten the healing time in the treatment of phimosis in children.