儿童社区获得性肺炎抗菌药物使用分析及合理性评价

Analysis of antimicrobial drug use of pediatric community acquired pneumonia

目的探讨本院儿童社区获得性肺炎抗菌药物使用情况,为指导合理使用抗感染药物提供参考。方法选择2014年6~12月住院治疗的98例儿童社区获得性肺炎,对患儿的基本信息以及相应抗菌药物使用种类、用法及疗程等信息进行归档分析。结果本研究中,所使用抗菌药物4类共7种,使用频次按高到低分别为阿奇霉素、哌拉西林他唑巴坦、阿莫西林克拉维酸钾,以静脉给药,其中两种抗菌药物联用共61例,占53.06%,人均抗菌药物住院费用为611.48元。结论本院在治疗儿童社区获得性肺炎住院过程抗菌药物使用基本合理,但其合理用药水平仍需要进一步提高。

Objective To analyze and evaluate the antimicrobial patients with pediatric community acquired pneumonia in our hospital.Method 98 cases of pediatric community acquired pneumonia in hospitalized patient were selected randomly from June to December 2014.The frequency of use of antibiotics,drug combination,drug costs,clinical effects were analyzed.Result There were four classes and seven kinds of antimicrobial used.The top three antibiotic drug used with high frequency were azithromyc,piperacillin sodium and tazobactam and amoxicillin sodium and clavulanate potassium.The routes of administration were intravenous injection and oral administration.Antibiotic therapy was mainly with two drugs combination,which was accounted for 84.70%.The total effective rate was 90.81%.The average cost of antibacterial drugs was 611.48 yuan in hospital children with CAP.Conclusion After the implementation of management of clinical application of antibacterial drugs,the antimicrobial drug use on hospitalized patients with pediatric community acquired pneumonia in our hospital is reasonable,but the rational use of drugs still need to be improved.