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化脓性肝脓肿伴发急性肾损伤的危险因素分析 被引量:5

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摘要 目的探讨化脓性肝脓肿(PLA)伴发急性肾损伤(AKI)的危险因素。方法回顾性分析554例PLA患者性别、年龄、伴发疾病、实验室检查指标、治疗及转归等资料,探讨PLA伴发AKI的危险因素。结果 PLA伴发AKI的发生率为12.3%(68/554),AKI 1、2、3期各占54.4%、20.6%、25.0%。PLA合并AKI患者(AKI组)年龄>65岁,合并高血压、胆道疾病,行肾脏替代治疗、发生感染性休克或死亡的比例均高于不伴有AKI患者(非AKI组)(P均<0.05),AKI组平均动脉压低于非AKI组(P<0.05)。AKI组白细胞、中性粒细胞比例、AST、尿素氮及血肌酐、国际标准化比值均高于非AKI组,血红蛋白、血小板计数、白蛋白、血钠、凝血酶原活动度、肾小球滤过率均低于非AKI组,两组比较P均<0.05。多因素Logistic回归分析显示,血肌酐升高、高血压、感染性休克是AKI发生的独立危险因素(OR分别为1.269、19.411、34.117,P均<0.05)。结论血肌酐升高、高血压、感染性休克是PLA伴发AKI的独立危险因素。
出处 《山东医药》 CAS 北大核心 2016年第8期49-51,共3页 Shandong Medical Journal
基金 "艾滋病和病毒性肝炎等重大传染病防治"科技重大专项课题(2012ZX10002004-011)
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参考文献15

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