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含地西他滨方案治疗80岁以上急性白血病患者四例并文献复习 被引量:3

Retrospective analysis of decitabine in the treatment of 4 acute leukemia patients older than 80 years and literature review
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摘要 目的:分析含地西他滨化疗方案对80岁以上急性白血病患者的疗效及安全性。方法应用含地西他滨化疗方案治疗80岁以上初发急性白血病患者4例,分析疗效及患者不良反应,并进行文献复习。结果4例患者共接受8个疗程治疗,不良反应轻微,患者耐受性良好。1个疗程完全缓解(CR)2例,2个疗程CR 1例,未缓解(NR)1例,生存时间33~225 d。主要不良反应为3~4级骨髓抑制、粒细胞缺乏、发热和肺炎。结论地西他滨可安全、有效地应用于老年急性白血病患者,可作为该类患者的治疗选择。
出处 《白血病.淋巴瘤》 CAS 2016年第2期121-124,共4页 Journal of Leukemia & Lymphoma
基金 广州市医药卫生科技项目(20151A010006)
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