焦虑对老年DMCI患者认知功能和颈动脉内膜-中层厚度的影响

EFFECTS OF ANXIETY ON COGNITIVE FUNCTION AND INTEIMA-MEDIA THICKNESS OF ELDERLY DMCI PATIENTS

目的:探讨焦虑对老年2型糖尿病合并脑梗死(DMCI)患者认知功能和颈动脉内膜-中层厚度(IMT)的影响。方法:100例老年DMCI患者根据是否存在焦虑分为观察组62例(合并焦虑)和对照组38例(不合并焦虑)。采用蒙特利尔认知评估量表(Mo CA)评价两组患者的认知功能,颈动脉超声检查测量IMT。结果:观察组患者IMT显著高于对照组、Mo CA评分显著低于对照组(P<0.01)。观察组患者焦虑评分与Mo CA评分呈负相关、与IMT呈正相关(P<0.01),Mo CA评分与IMT呈负相关(P<0.01)。结论:合并焦虑可加重DMCI患者的认知功能障碍及颈动脉粥样硬化程度,导致患者生活质量下降。

Objective： To investigate the effects of anxiety on cognitive function and intima-media thickness （IMT） of elderly patients with type 2 diabetes complicated with cerebral infarction （DMCI）. Methods： 100 elderly DMCI patients were divided into observation group （n=62, with anxiety） and control group （n=38, no anxiety）. MoCA scale was used to evaluate the cognitive function of patients, and color ultrasound to measure IMT of common carotid artery. Results： IMT of patients in observation group was obviously higher than patients in control group, but MoCA score was obviously lower （P〈0.01）. The anxiety score of patients in observation group was negatively correlated with MoCA score, but positively correlated with IMT （P〈0.01）; And MoCA score was negatively correlated with IMT （P〈0.01）. Conclusions： Anxiety may aggravate cognitive dysfunction and degree of carotid atherosclerosis, and cause declining of the living quality.