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衢州市健康人群百日咳抗体水平监测分析 被引量:5

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摘要 目的监测衢州市健康人群百日咳抗体,为制订科学的免疫方案和提高接种质量提供依据。方法分新生儿、2岁、3岁、4~5岁、6~7岁、8~10岁、11~15岁、16~25岁、26~35岁、36~59岁和≥60岁共11个年龄组,按随机抽样方法抽取30~50名监测对象,共采集357名健康人血清,采用Ig G抗体定量检测试剂盒(酶联免疫法)测定百日咳PT-Ig G。结果百日咳PT-Ig G抗体总阳性率为26.61%,百日咳各年龄组阳性保护率和GMC差异均有统计学意义(P〈0.01)。结论百日咳PT-Ig G抗体阳性率较高,反映出取得了明显的流行病学效果,衢州市百日咳疫苗免疫接种有效。
出处 《中国公共卫生管理》 2016年第1期94-95,98,共3页 Chinese Journal of Public Health Management
基金 衢州市科学技术局科技计划项目(2013096)
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  • 1Relman DA, Domenighini M,Tuomanen E,et al. Filamentous hemagglutinin of Bordetella pertusssis: nucleotide sequence and crucial role in adherence. Pcoc Natl Acad Sci USA, 1989,86:2637-2641.
  • 2Sato Y, Cowell L,James L,et al.Separation and pufication of the hemagglutinins from bordetella pertussis. Infect Immun, 1983,41(1):313-320.
  • 3Frigues B,Chaffotte AF, Djavadi-Ohaniame L,et al. Measurements of the true affinity constant in solution of antigen-abtibody complexes by enzyme-linked immunosorbent assay. J Immun Mtd, 1985,77:305-319.
  • 4Ta T,Trindade E,Skowronski D.Epidemiology of pertussis[J].The pediatric infectious disease journal,2005,24(5):10-18.
  • 5WHO.Pertussis[EB/OL].[2014-6-20].
  • 6Beest DE,Henderson D,Maas NA,et al.Estimation of the serial interval of pertussis in Dutch households[J].Epidemics,2014,7:1-6.
  • 7Sizaire V,Estepa MG,Calles JM,et al.Increase of pertussis incidence in 2010 to 2012 after 12 years of low circulation in spain[J].Euro surveillance,2014,19(32).
  • 8Littmann M,Hulbe C,Riffelmann M,et al.Long-term immunogenicity of asingle dose of acellular pertussis vaccine in paediatric health-care workers[J].Vaccine,2008,26:2344-2349.
  • 9Prince HE,Lieberman JM,Cherry JD.Age-related differences in patterns of increased Bordetella pertussis antibodies[J].Clinical and vaccine immunology,2012,19(4):545-550.
  • 10Zhang Q,Han F,Nie Q,et al.Seroprevalence of antibodies to pertussis and diphtheria among healthy adults in China[J].Journal of infection.2011,63(6):441-446.

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