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胶质瘤的综合治疗及围术期护理进展 被引量:4

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摘要 胶质瘤是最常见的中枢神经系统原发肿瘤,约占颅内肿瘤的一半。基于病理学特征,WHO将胶质瘤分为Ⅰ-Ⅳ级,其中Ⅰ级和Ⅱ级胶质瘤统称为低级别胶质瘤,Ⅲ级和Ⅳ级胶质瘤统称为高级别胶质瘤。近60%的高级别胶质瘤为胶质母细胞瘤( GBM),其最常见的成人恶性胶质瘤类型,占颅内肿瘤的17%,发病率约为3/10万。GBM的标准治疗为手术联合同步放化疗。但是,由于肿瘤的广泛浸润及快速增殖,GBM患者的生存期约为1年(12-14个月),5年生存率仅为9.8%。Ⅱ和Ⅲ级胶质瘤的预后相对较好,术后的生存期分别为2-5年和2年。不良的预后促进了相关的临床和基础研究,现将胶质瘤近年的治疗进展作一综述。
出处 《中华现代护理杂志》 2015年第36期4341-4344,共4页 Chinese Journal of Modern Nursing
基金 北京市卫生系统高层次人才培养计划(2014-2-008)
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