不同日龄新西兰白兔血液学特性研究

Experimental Study on Hematological Parameters of New Zealand White Rabbits at Different Ages

目的 探讨不同日龄封闭群新西兰白兔的血液学特性.方法 采集不同年龄、不同性别新西兰白兔的血液样品,应用全自动血细胞仪测定160只新西兰白兔的血液学指标.结果 各年龄段新西兰白兔血液学指标性别间无显著差异（P＞0.05）,不同年龄段之间除单核细胞总数差异不显著（P＞0.05）,其它指标有显著差异（P＜0.05）.结论 本院培育自繁的实验型封闭群新西兰白兔生物学特性较稳定,个体间差异较小,初步建立了不同日龄新西兰白兔血液生理指标正常值,为新西兰白兔的广泛使用提供基础数据.

Objective To investigate the hematological parameters of outbred colony New Zealand white rabbits at different ages. Methods Blood samples from 160 New Zealand white rabbits （Female, 80 and male, 80） in different age groups were analyzed with automatic blood cell analyzer. Result There was no statically significant difference between the blood samples of different age experimental closed colony New Zealand white rabbits in different sex sets （P〉0.05）. Significant differences （P〈0.05） of hematological indexes except monocyte （P〉0.05） were observed among New Zealand white rabbits in different age groups. Conclusion The outbred colony New Zealand white rabbits had stable biological characteristics and less difference among individuals. In this study, the biological hematologic parameters database for New Zealand white rabbits at different ages was established, which will be used as basic reference for New Zealand white rabbits experiment.