生命早期室内环境暴露与儿童哮喘的关系

Relationship between early life exposure to indoor environment and childhood asthma

哮喘是最常见的慢性疾病之一,其病因复杂并具有多基因遗传倾向,是由多种细胞和细胞组分参与的气道慢性炎症性疾病。研究表明,生命早期的某些室内环境暴露与儿童期甚至成人期哮喘的发病存在一定的相关性,如室内油烟、湿度、尘螨等暴露。该综述就生命早期室内环境暴露对儿童哮喘的影响进行讨论,并提出相应的干预措施,旨在为哮喘预防和控制措施的制定提供参考。

Asthma,caused by complicated pathogens,is one of the most common chronic diseases,and is polygenic inheritance. It is a kind of airway chronic inflammatory disease,and a variety of cells and cellular components are involved. It has been suggested that exposure of early life to certain indoor environments,such as indoor oil,humidity,and house mites is correlated with asthma in childhood and even in adulthood. The review analyzes and discusses the impact of early life exposure to indoor environment on children asthma. Besides,the corresponding intervention measures are put forward to provide some references for the prevention and control of asthma.