苦黄注射液对急性黄疸型肝炎患者肝功能及血清微量元素水平影响

Kuhuang injection on liver function and serum trace elements levels in patients with acute jaundice hepatitis

目的探究苦黄注射液对急性黄疸型肝炎患者肝功能及微量元素水平影响。方法收集2013年12月~2015年4月于衢州市人民医院感染科治疗的急性黄疸型肝炎患者37例,随机分为治疗组与对照组,对照组19例采用门冬氨酸钾镁注射液,治疗组18例,在对照组基础上加用苦黄注射液。比较患者治疗前肝功能及微量元素水平。结果治疗后与对照组相比,治疗组血清甘胆酸（serum cholyglycine,SCG）水平较低（P〈0.05）;血清总胆红素（total bilirubin,TBIL）、直接胆红素（direct bilirubin,DBil）水平较低（P〈0.05）;镁、铜、锌水平较高（P〈0.05）;铁水平较低（P〈0.05）。结论苦黄注射液对急性黄疸型肝炎患者具有较好的临床疗效,推测其机制与改善患者肝功能及血清微量元素水平有关。

Objective To explore the effect of Kuhuang injection on liver function and serum trace elements levels in patients with acute jaundice hepatitis. Methods 37 cases of acute jaundice hepatitis patients from December 2013 to April 2015 were selected and randomly assigned into treatment group and control group,19 cases in control group were treated with potassium magnesium aspartate injection,18 cases in treatment group with Kuhuang injection on the basis of control group. The liver function and serum trace elements were compared pre-and post-treatment. Results Compared with control group post-treatment,the level of serum cholyglycine（ SCG） was significantly lower（ P〈0. 05）,the levels of total bilirubin（ TBIL） and direct bilirubin（ DBil） were lower（ P〈0. 05）,magnesium,copper,zinc levels were higher（ P〈0. 05） and level of iron were lower（ P〈0. 05） in treatment group. Conclusion Kuhuang injection has good clinical curative effect for the patients with acute jaundice hepatitis,we speculated that it might be possible to improve the liver function and levels of serum trace elements.