拟除虫菊酯杀虫剂的毒性和健康危害研究进展

A Review on the Toxicity of Pyrethroid Pesticides and Their Harms to Population Health

在现今世界范围内,拟除虫菊酯杀虫剂已被广泛应用于防治农业病虫害以及用作室内杀虫剂,因此对人类日常生活产生重要影响。拟除虫菊酯杀虫剂的急性毒性研究已经有较多成果和进展,但对其长期慢性影响至今仍缺乏明确论证。此综述从Pub Med、EBSCO和中国知网等数据库收集了国内外已发表的、有关拟除虫菊酯杀虫剂的动物实验、人群调查和实验室检验的长期、慢性影响的典型研究论文,并从中筛选出拟除虫菊酯杀虫剂的神经毒性、生殖发育毒性、免疫毒性与肿瘤研究等方面的研究进展,综述长期接触拟除虫菊酯杀虫剂可能对人体产生的神经、生殖及免疫系统方面的危害,为进一步研究和开发无害化农药杀虫剂提供参考思路。

Currently, pyrethroid pesticides have been widely used as insect killers in agricultural field and indoor environment worldwide, thus yielding an important impact on daily life of the public. The long-term and chronic effects of pyrethroid pesticides remain unreported in spite of studies on their acute toxic effects. Based on the related publications indexed by Pub Med, EBSCO and China National Knowledge Infrastructure（CNKI）, we summarized the findings of researches on toxic experiments, investigations, and laboratory tests regarding to pyrethroid pesticides up to today. In conclusion, long-term exposure to pyrethroid pesticides may have toxic effects onnervous system, reproductive system and immune system.In addition, long-term exposure to pyrethroidpesticides may cause tumors. Thisreview provides directions and ideas for future studies.