血小板凝胶在颅脑手术中的临床应用

Clinical application of platelet gel to neurosurgery

目的探讨可吸收材料血小板凝胶在颅脑手术中的应用效果。方法选取2013年10月至2014年3月行颅脑手术的患者120例(凝血机制均无明显异常),分为观察组和对照组,各60例;观察组术中应用血小板凝胶加明胶海绵用于手术创面止血,对照组单独用明胶海绵进行常规止血。结果观察组术后24 h出血量([35±10)ml]明显少于对照组([110±12)ml(]P<0.05)。观察组瘤腔、血肿腔术后渗血量([5±4)ml]也明显少于对照组([20±15)ml(]P<0.05)。结论可吸收材料血小板凝胶在颅脑手术中有良好的止血效果,并且具有很好的安全性,配合常规止血材料使用,方便易用。

Objective To investigate the effect of absorbable platelet gel on neurosurgical operation.Methods One hundred and twenty neurosurgical patients with normal coagulation function were randomly divided into observed group（n=60） and control group（n=60）. The platelet gel combined with gelatin sponge serving as hemostatic was intraoperatively applied to open wound in the observed group and only gelatin sponge in the control group. The intraoperative and postoperative hemostatic effects 24 hours after the operation were observed.Results The volume[（110±12） ml ]of drained blood was significantly more in the control group than that[（35±10） ml]in the observed group 24 hours after the operation（P〈0.05）. The volume[（20±15） ml]of the blood remaining in the residual cavity was significantly more in the control group than that[（5 ± 4） ml]in the observed group（P〈0.05）.Conclusions The absorbable hemostatic material platelet gel which has a good hemostatic effect on bleeding caused by neurosurgical operation and is of the merits such as safety and easy use, should be recommended to be used clinically in the neurosurgical patients..