新型尘螨过敏原疫苗的研究进展

Advance in research on novel vaccine against dust mite allergens

尘螨是导致过敏性哮喘、鼻炎和皮炎等过敏性疾病重要的过敏原来源。脱敏治疗是目前治疗过敏性疾病最为有效的手段。随着对过敏原研究的日益深入,过敏原疫苗的研究越来越得到重视。本文对预防治疗尘螨过敏原相关疾病的DNA疫苗、重组活菌疫苗、重组蛋白疫苗及细菌性疫苗等新型疫苗的研究进展作一简要综述,旨在为过敏原相关疾病的防控提供参考。

Dust mite is an important cause for anaphylactic diseases such as allergic asthma, rhinitis and dermatitis. At present, desensitization is the most effective way for the anaphylactic diseases. Along with the increasing research on al-lergens, allergen vaccines are paid more and more attentions. This article focuses on advance in novel vaccines of dust mite allergens, such as DNA vaccine, recombinant bacterial vaccine, recombinant protein vaccine and bacterial vaccine,aiming to provide a reference for prevention and control of allergen-associated diseases.