肿瘤微创消融新技术——不可逆性电穿孔

A New and Minimally Invasive Ablation Technology for Tumors——Irreversible Electroporation

目的总结肿瘤微创消融新技术——不可逆性电穿孔的临床应用。方法对国内外相关文献进行综述分析。结果不可逆性电穿孔与传统消融技术相比,具有界限清晰、组织选择性好、不受血流热/冷吸除作用影响、消融时间短等优点,在合并其他疾病无法耐受手术、晚期不适合行手术切除及直径在3 cm以下的实质性肿瘤患者的治疗中发挥重要作用。结论不可逆性电穿孔作为一种肿瘤微创消融新技术,具有极高的安全性和有效性。

Objective To summary the clinical application of a new and minimally invasive ablation technology for tumors—irreversible electroporation. Methods Related domestic and foreign literatures were reviewed. Results Compared with traditional ablation technology, irreversible electroporation had advantages of complete ablation with well-demarcated margin, preservation of vital structures, avoidance of heat/cold-sink effect, and short ablation time. Irreversible electroporation may play an import role in patients who couldn’t tolerate surgery in reason of combining with other disease, who were not suitable for surgery due to late tumors, and who had solid tumors of less than 3 cm in diameter. Conclusion As a new and minimally invasive ablation technology for tumors, irreversible electroporation has high safety and efficacy.