颈围与肥胖相关指标及胰岛素抵抗相关代谢紊乱的关系研究

A study on the relationship between neck circumference and obesity related indexes and metabolic disordersassociated with insulin resistance

目的探讨颈围与肥胖相关指标及胰岛素抵抗相关代谢紊乱之间的关系。方法采用整群随机抽样法以任丘市年龄60～70岁的常住居民4412例为调查对象，进行面对面健康问卷调查、体格检查、实验室检测。根据男女性别分组，分析颈围与肥胖相关指标及胰岛素抵抗相关的代谢紊乱之间的相关性。结果男性与女性调查者颈围、腰围、腰身比、BMI比较，差异均有统计学意义（t=34．686、3．879、-16．224、-6．304，均P〈0．05）；颈围与腰围、腰身比、BMI均呈显著正相关（男：r=0．752、0．695、0．761，女：r=0．707、0．655、0．721，P〈0．01）。颈围、腰围、腰身比及BMI等肥胖相关指标的增高趋势分别与高血压、糖尿病、高脂血症及高胰岛素血症的增高趋势相吻合，且无性别差异，随着颈围水平的增加，上述疾病的发生率亦相应增加。结论颈围与肥胖相关指标及胰岛素抵抗相关的代谢紊乱有关，颈围测量可作为中心性肥胖的有效测量指标，对临床胰岛素抵抗相关的代谢紊乱的早期预测及预防有重要意义。

Objective To investigate the potential relationship between neck circumference and obesity related indexes and metabolic disorders associated with insulin resistance. Methods A random cluster sampling method was used to identify study population among the 4 412 60 - 70 years old permanent residents in Renqiu region. Face to face health questionnaire, physical examination, laboratory tests were used. According to the gender group, the correlation between neck circumference and obesity related indexes and metabolic disorders associated with insulin resistance were analyzed. Results Comparing neck circumference and waist circumference,waist height ratio, and body mass index（BMI） of man and woman respondents, the differences were statistically significant. Neck circum- ference and waist circumference, waist height ratio, and BMI had positive correlation （ male ： r = 0. 752,0. 695 and 0. 761. W：r = 0. 707 ,0. 655 ,0. 721, all P 〈 0.01 ）. Increased trends of neck circumference, waist circumference, waist height ratio and BMI coincided with increased trend of thypertension, diabetes, hypedipidemia and hyperinsulinemia and hyperlipidemia, and no gender differences. With the increase of the neck circumference, the incidence of above mentioned diseases also increased accordingly. Conclusion Neck circumference was associated with obesity related indexes and metabolic disorders associated with insulin resistance. Neck circumference measurement can be used as an effective indicator of Central obesity, and had great significance for early prediction and prevention of metabolic disorders associated with clinical insulin resistance.