肾嫌色细胞癌的诊断和治疗

Diagnosis and therapy of renal chromophobe cell carcinoma

目的：探讨肾嫌色细胞癌（renal chromophobe cell carcinoma,RCCC）的临床特征、病理学特点、诊断、治疗方法和预后。方法：回顾性分析2010年2月至2015年4月期间经病理检查证实的11例RCCC患者的临床资料,结合相关文献复习并进行讨论。结果：11例患者中7例男性,4例女性,年龄40~71岁,平均59岁。肿物直径3.5~14.5cm。病变位于右侧者6例,左侧5例。术前无症状者6例,单纯性腰背部疼痛不适5例。11例患者均经CT检查确诊,均行手术治疗。手术过程顺利,术后均有病理证实为肾嫌色细胞癌。出院后随访3~36个月,无肿瘤复发和转移。结论：RCCC是一种低度恶性,少见的肾脏肿瘤。手术治疗是首选方法,预后较好。

Objective： To investigate the clinical features, pathological characteristics, diagnosis, treatment and prognosis of renal chromophobe cell carcinoma（RCCC）. Methods：Clinical data of 11 cases of RCCC were analyzed retrospectively and pertinent literatures were reviewed. Results：Seven cases were males and 4 cases were females, aged 40 -71, averaged 59 years old. Bump diameter 3.5 - 14.5cm. 6 cases were on the right kidney and the other cases were on the left side. 6 cases had no symptoms,5 cases complained about simple backache. 11 cases were all taken CT scan for diagnosis and undertaken open or laparoscopic surgery. During 3 to 36 months follow -up, no tumor relapse. Conclusion ：RCCC is a low grade rare renal tumor and the treatment mainly depends on the surgery. Surgery was the preferred method of treatment, and the prognosis is good.