摘要
目的探讨晚期前列腺癌患者行间歇性内分泌治疗的临床效果。方法选取2013年8月~2014年12月在我院住院治疗的98例前列腺癌患者进行研究,分为间歇组和持续组,并比较两组患者的临床疗效以及不良反应发生率。结果间歇性和持续性内分泌组患者其血清中PSA水平、排尿梗阻症状以及疼痛情况均较治疗前好转（P〈0.05）;同时间歇性内分泌治疗组患者不良反应发生率以及生活质量评分优于持续组（P〈0.05）。结论间歇性和持续性内分泌疗法在治疗晚期前列腺癌患者方面其临床治疗效果相当,但间歇性内分泌疗法在缓解患者疼痛和临床症状以及提高生活质量方面更有优势。
Objective Discussion on therapy clinical results of advanced prostate cancer patients intermittent hormonal. Methods Selected 98 cases of prostate cancer from August 2013 to December 2014 in our hospital, which were divided into groups and continued intermittently group, compared the clinical efficacy and the incidence of adverse reactions of two groups. Results Intermittent and persistent endocrine patients whose serum PSA levels before urination obstructive symptoms and pain were significantly improved than before treatment（P〈0.05）, while intermittent hormonal therapy in patients whose incidence of adverse reactions and quality of life scores were significantly better than the continuous group（P〈0.05）. Conclusion Continuous and intermittent endocrine therapy in the treatment of advanced prostate cancer patients whose clinical outcomes equivalent, but intermittent endocrine therapy more advantages in relieving pain and clinical symptoms and improve quality of life.
出处
《中国继续医学教育》
2016年第6期100-101,共2页
China Continuing Medical Education
