熵指数在老年全身麻醉患者中的应用效果

Application of entropy in the elderly patients underwent general anaesthesia

目的:观察熵指数在老年患者全身麻醉中的应用效果。方法:80例实施全身麻醉(全麻)的老年患者,随机分为两组:熵指数组和对照组。熵指数组依据熵指数值调节异丙酚和瑞芬太尼输注速度,对照组根据患者血压、心率、来调节异丙酚和瑞芬太尼输注速度。记录两组患者插管前、插管时和切皮时的平均动脉压(MAP)与心率(HR),记录两组患者异丙酚用量、瑞芬太尼用量和术后苏醒时间。结果:熵指数组患者插管时、切皮时的血压、心率均比对照组的低,差异有统计学意义(P<0.05);熵指数组患者异丙酚和瑞芬太尼用量比对照组少,差异有统计学意义(P<0.05),而苏醒时间短于对照组,差异有统计学意义(P<0.05);此外,两组患者的不良反应发生率相当。结论:老年患者行全身麻醉时应用熵指数调控麻醉深度,可使患者血流动力学更稳定,患者麻醉药用量更少、苏醒时间更短。

Objective To observe the effect of entropy in the elderly patients underwent general anaesthesia. Method Eighty elderly patients underwent general anaesthesia were divided into two groups： Entropy group and Control group. The transfusion rate of propofol and remifentanil was adjusted according to entropy in Entropy group. The transfusion rate of propofol and remifentanil was adjusted according to BP,HR in Control group. The MAP and the HR of before tracheal intubation,during tracheal intubation,during skin incision were recorded in both groups. The dosage of propofol and remifentanil were recorded in both groups. The time of revival were recorded in both groups. Results The MAP and the HR of during tracheal intubation,during skin incision in Entropy group were lower than that in Control group,the difference was statistically significant（ P〈0. 05）. The dosage of propofol and remifentanil in Entropy group were less than that in Control group,the difference was statistically significant（ P〈0. 05）. The time of revival in Entropy group was shorter than it in Control group,the difference was statistically significant（ P〈0. 05）. In addition,there were not significant difference in complications between two groups. Conclusion Application of entropy in the elderly patients underwent general anaesthesia,which makes the MAP and HR more steady,the dosage of propofol less and the time of revival shorter.