期刊文献+

脑小血管病血浆神经肽Y、同型半胱氨酸相关性研究 被引量:3

下载PDF
导出
摘要 目的:探讨脑小血管病(CSVD)与神经肽Y(NPY)、血浆同型半胱氨酸(Hcy)水平的相关性。方法:选取182例脑小血管病患者作为观察组,选取30例健康志愿者作为对照组,测定两组血浆NPY、Hcy浓度,进行比较分析。结果:观察组NPY、Hcy浓度分别为(182.65±38.33)pg/ml、(19.24±5.98)μmol/L,高于对照组的(131.03±31.04)pg/ml、(12.67±4.93)μmol/L,组间差异有显著统计学意义(P<0.01)。结论:脑小血管病患者NPY、Hey水平明显高于对照组,表明NPY、Hey参与了脑小血管病的发病过程,临床检测和干预有一定意义。
出处 《吉林医学》 CAS 2016年第3期686-687,共2页 Jilin Medical Journal
  • 相关文献

参考文献5

二级参考文献54

  • 1傅建辉,黄家星.合并小血管病的颅内大动脉狭窄患者的预后[J].神经病学与神经康复学杂志,2010,7(1):12-16. 被引量:18
  • 2俞羚,董荃,宋叶平,江静雯,李卉,刘亮贤,苏爱萍,李焰生,Sacco RL,Kasner SE,Broderick JP,Caplan LR,Connors JJ,Culebras A,Elkind MS,George MG,Hamdan AD,Higashida RT,Hoh BL,Janis LS,Kase CS,Kleindorfer DO,Lee JM,Moseley ME,Peterson ED,Turan TN,Valderrama AL,Vinters HV.面向21世纪的卒中新定义:美国心脏病学会和美国卒中学会声明[J].神经病学与神经康复学杂志,2013,10(2):105-120. 被引量:203
  • 3张金玉.MTHFR基因多态性与腔隙性脑梗死的相关性研究[J].山东医药,2005,45(19):26-27. 被引量:9
  • 4各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33022
  • 5Frosst P, Blom HJ, Milos R, et al.A candidate genetic risk factor for vascular discase:a common mutation in mcthy/enetetrahydrofolate reduetase [ J ]. Nat Genet, 1995,10 ( 1 ) : 111-113.
  • 6Eikelboom JW, Hankey GJ, Anand SS, et al. Association between homocysteine and ischcmic stroke due to large-and small- artery disease but not other etiologic subtype of ischemic stroke[ J]. Stroke, 2000,31 (5) : 1069-1075.
  • 7Li Z, Sun L, Zhang H, et al. Elevated plasma homocysteine was associated with hemorrhagic and ishcemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorp-hism was a risk factor for thrombotic stroke: a Muhicenter case-control study in China[ J]. Stroke, 2003,34(9) :2085-2090.
  • 8Fiso S, Girelli D, Trabetti E, et al. A1298C methylenetetrahydrofolate reductase mutation and coronary artery disease: relationships with C677T polymorphism and homocysteine/folate metabolism[ J]. Clin Exp Med, 2002,2( 1 ) :7-12.
  • 9Hamelahti P, Jarvinen O, Sisto T, et al. Methylenetetrahydrofolate reductase gene C677T mutation is related to the defects in the internal elastic lamina of the artery wall[ J]. Eur J Clin Invest, 2002, 2 ( 17 ) :869-873.
  • 10O' Sullivan M,Morris RG, Markus HS. Brief cognitive assessment for patients with cerebral small vessel disease[ J ]. Neurol Neurosurg Psy- chiatry ,2005,76 : 1140 - 1145.

共引文献161

同被引文献44

引证文献3

二级引证文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部