头孢呋辛钠联合清开灵治疗肺气肿感染疗效及不良反应分析

The Analysis of Curative Effect of Cefuroxime Sodium on Pulmonary Emphysema Infection Combined with Qingkailing Compound and Relevant Adverse Effects

目的探讨研究联合使用头孢呋辛钠与清开灵治疗肺气肿感染的临床疗效,并评价其安全性。方法随机选取52例我院自2013年2月份至2015年8月份收治的老年肺气肿感染患者,均分为对照组和实验组两组,对照组患者注射头孢呋辛钠,实验组在头孢呋辛钠基础上注射清开灵,一个疗程后,观察记录两组患者的起效时间、疗效情况、体温恢复正常时间以及X线片结果显示正常时间,并统计两组不良反应的发生情况。结果实验组的总有效率为92.3%,明显高于对照组(73.1%),实验组在起效时间、身体指标恢复时间与X线片结果显示正常时间均早于对照组,而不良反应发生情况明显少,具有统计学差异(P<0.05)。结论联合使用头孢呋辛钠与清开灵治疗老年肺气肿感染比单纯使用头孢呋辛钠的临床疗效明显,副作用小,安全可靠,值得在临床上广泛推广应用。

Objective The clinical effects of cefuroxime sodium on pulmonary emphysema infection combined with Qingkailing compound was investigated and its safety was evaluated. Methods Fifty-two geriatric patients who were receiving pulmonary emphysema infection treatment in our hospital from February to August of 2015 were selected on a random basis and divided into two groups： control group and experimental group. The patients in the control group received cefuroxime sodium injection only, while the patients in the experimental group received Qingkailing compound injection in addition to cefuroxime sodium one, and the onset time, curative effect, the time for body temperature to go normal and the time that X-ray film results showed normal were recorded, and the occurrences of adverse effects were counted. Results The total effective rate for the experimental group was 92.3%, evidently higher than the control group （73.1%）, and the onset time, the time for body indexes to return normal and the time that X-ray film results showed normal were all earlier than that in the control group, while the occurrence of adverse effects was remarkably lower, as to which, the two group exhibited a statistical significance （P 〈 0.05）. Conclusion Cefuroxime sodium combined with Qingkailing compound can achieve more evident clinical effects than when only cefuroxime sodium injection has been taken, and has less adverse effects, thus worth generally promoting in clinical applications for its safety and reliability.