期刊文献+

促甲状腺激素受体与甲状腺癌的研究进展 被引量:5

Review of thyroid stimulating hormone receptor and thyroid carcinoma
原文传递
导出
摘要 甲状腺癌是内分泌系统最常见的恶性肿瘤,发病率在持续提高。随着对甲状腺癌的深入研究,促甲状腺激素受体逐渐被世人所发现,且其与甲状腺癌的发展,有着千丝万缕的关联。我们相信,通过研究促甲状腺激素受体与甲状腺癌的关系,可以为患者的诊断、治疗,乃至预后提供一个有效的切入点。 Thyroid carcinoma is the most common malignant tumor in the endocrine diseases, with a rising morbidity. As more investigations were made, thyroid stimulating hormone receptor is showed up, and it is believed some contacts are existed between thyroid stimulating hormone receptor and thyroid carcinoma. We be lieve that making sure of these contacts can help patients in diagnosis, treatment, and prognosis.
出处 《中华内分泌外科杂志》 CAS 2016年第1期74-77,共4页 Chinese Journal of Endocrine Surgery
关键词 甲状腺癌 促甲状腺激素受体 Thyroid carcima Thyroid stimulating hormone recptor
  • 相关文献

参考文献31

  • 1Pelizzo MR, Dobfinja C, Casal Ide E, et al. The role of BRAF (V60OE)mutation as poor prognostic factor for the outcome of patients with intrathyroid papillary thyroid carcinoma[J]. Biom Pharm,2014, 68(4):413-7. DOI:10.1016/j.biopha.2014.03.008.
  • 2Garca-Jimnez CI, Santisteban P. TSH signaling and cancer[J]. Arq Bras Endocrinol Metab,2007,51 (5):654-671. DOI:10.1590/ S0004-27302007000500003.
  • 3Parmentier M, Libert F, Maenhaut C, et al. Molecular cloning of the thyrotropin receptor[J]. Science,1989,22:1620-1622. DOI:10.1126/ science.2556796.
  • 4Misrahi M, Loosfelt H, Atger M, et al. Cloning, sequencing and expression of human TSH receptor[J]. Biochem Biophys Res Commun, 1990,166(1):394-403. DOI:10.1016/0006-291X(90)91958-U.
  • 5Rousseau-Merck MF, Misrahi M, Loosfelt H, et al. Assignment of the human thyroid stimulating hormone receptor (TSHR)gene to chromosome 14q31[J]. Genomics,1990,8(2):233-236. DOI:10.1016/ 0888-7543 (90)90276-Z.
  • 6Galofre JC, Chacen AM, Latif R. Targeting thyroid diseases with TSH receptor analogs[J]. Endocr Nutr,2013,60 (10):590-598. DOI: 10.1016/j.endonu.2012.12.008.
  • 7Francoa AT, Malaguarneraa R, RefetofPo S, et al. Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice[J]. PNAS,2011,108(4):1615-1620. DOI:10.1073/pnas.10155 57108.
  • 8Davies T, Marians R, Latif R. The TSH receptor reveals itself[J].J Clin Invest,2002,110(2):161-164. DOI:10.1172/JCI16234.
  • 9Hegedtis L. The thyroid nodule[J]. N Engl J Med,2004,351:1764- 1771. DOI: 10.1056/NEJMep031436.
  • 10Takano T. Fetal cell carcinogenesis of the thyroid: a hypothesis for better understanding of gene expression profile and genomic alternation in thyroid carcinoma [J]. Endocr J,2004,51 (6):509- 515. DOI: 10.1507/endocrj.51.509.

二级参考文献66

  • 1李咏梅,曹芳,曹新.乳腺癌RASSF1A基因表达及启动子区甲基化研究[J].南京医科大学学报(自然科学版),2006,26(7):496-500. 被引量:9
  • 2李敏,黄在菊,董卫红,李晓艳,王晓翊,贺晓红,王瀚,王泽华.卵巢上皮性癌组织中p16INK4A基因表达缺陷的意义及其与甲基化的关系[J].中华妇产科杂志,2006,41(6):408-412. 被引量:8
  • 3Das PM,Singal R.DNA methylation and cancer.J Clin Oncol,2004,22:46324642.
  • 4Xing M,Usadel H,Cohen Y,et al.Methylation of the thyroid-stimulating hormone receptor gene in epithelial thyroid tumors-a marker of malignancy and a cause of gene silencing.Cancer Res,2003,63:2316-2321.
  • 5Xing M,Cohen Y,Mambo E,et al.Early occurrence of RASSF1A hypermethylation and its mutual exclusion with BRAF mutation in thyroid tumorigenesis.Cancer Res,2004,64:1664-1668.
  • 6Boltze C,Zack S,Quednow C,et al.Hypermethylation of the CDKN2/ pl6 INK4 A promoter in thyroid carcinogenesis.Pathol Res Pract,2003,199=399404.
  • 7Smith JA,Fan CY,Zou C,et al.Methylation status of genes in papillary thyroid carcinoma.Arch Otolaryngol Head Neck Surg,2007,133:1006-1011.
  • 8Schagdarsurengin U,Gimm O,Dralle H,et al.CpC island methylation of tumor-related promoters occurs preferentially in undifferentiated carcinoma.Thyroid,2006,16:633-642.
  • 9Schagdarsuregin U,Gimm O,Hoang-Vu C,et al.Frequent epigenetic silencing of the CpG island promoter of RASSF1A in thyroid carcinoma.Cancer Res,2002,62:3698-3701.
  • 10Byun DS,Lee MG,Chae KS,et al.Frequent epigenetic inactivation of RASSF1A by aberrant promoter hypermethylation in human gastric adenocarcinoma.Cancer Res,2001,61:7034-7038.

共引文献35

同被引文献64

引证文献5

二级引证文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部