腹部肿瘤锥形束计算机断层扫描图像引导放射治疗最优图像配准方法的选择与评价

Selection and evaluation of optimal image registration method based on cone beam computed tomography image guided radiation therapy for abdominal tumor

目的探讨腹部肿瘤锥形束计算机断层扫描(CT)图像引导放射治疗的最优图像配准方法。方法选取收治的腹部肿瘤患者18例,在线引导下均行千伏特锥形束CT(KVCBCT)体位校正,收集校正图像,分别采用基于灰度自动配准、骨性结构自动配准、人工图像配准及自动+手动配准方法对计划CT图像及KVCBCT图像配准,选择与评价最优配准方法。结果与其他配准方法比较,自动+手动配准方法图像配准评分较高,配准较准确,差异有统计学意义(P<0.05)。结论腹部肿瘤在线引导下以自动+手动配准方法配准度较高,且重复性较强,临床值得普及。

Objective To explore the best image registration method based on cone beam computed tomography image guided radiation therapy for abdominal tumor. Methods A total of 18 cases of abdominal tumor patients in our hospital were selected,online guided underwent kilovoltage cone beam CT for kvcbct position correction,collected image correction,and respectively used gray-based automatic registration,bone-based automatic registration,manual registration,automatic and manual registration method to compare the registration of planning CT images and KVCBCT image,selected and evaluated the optimal registration method. Results Compared with other registration method,automatic ＋ manual registration method had higher score,it was more accurate,and the difference was statistically significant（ P〈0. 05）.Conclusion Automatic ＋ manual registration method is relatively more accurate,and it has a good reproducibility,so it is worthy of clinical popularization.