摘要
动脉粥样硬化作为慢性炎症性疾病,可导致心肌梗死、脑卒中和外周动脉疾病。程序性坏死是近年来提出的新型细胞死亡形式,被认为是一种程序化的坏死,或可调控的非凋亡性细胞死亡方式,可以介导机体炎症反应的发生,参与多种炎症性疾病的病理过程。研究表明,程序性坏死参与了动脉粥样硬化斑块的形成,且可促进动脉粥样硬化斑块进展。
Atherosclerosis is a chronic inflammatory disease of the vasculature that causes myocardial infarction,stroke and peripheral vascular disease. Necroptosis is a newly identified type of cell death that has been considered as a form of programmed necrosis or regulated nonapoptotic cell death which may trigger inflammation and is involved in many inflammatory diseases. Researches have shown that necroptosis contributes to the formation and development of atherosclerosis.
出处
《心血管病学进展》
CAS
2016年第2期139-142,共4页
Advances in Cardiovascular Diseases
基金
国家自然科学基金资助项目(81371709)
