摘要
每年约有2.5%的发作性偏头痛转化为慢性偏头痛。偏头痛慢性化的机制不清楚,可靠的动物模型有助于慢性偏头痛发病机制的研究及其防治药物的研发。本文从理论依据、造模方法、观察指标、模型评价等方面对慢性偏头痛的动物模型研究进展进行综述。
About 2.5% of people with episodic migraine transform to chronic migraine every year. Till now, the mechanisms of transformation remain unclear. A reliable animal model of chronic migraine will be beneficial to understand the pathogenesis of migraine and drug development. Here, we comprehensively summarize literatures about the experimental animal models with chronic migraine.
出处
《解放军医学院学报》
CAS
2016年第3期286-288,297,共4页
Academic Journal of Chinese PLA Medical School
基金
国家自然科学基金面上项目(81471147)~~
关键词
慢性偏头痛
模型
动物
chronic migraine
model
animal
