317例胃癌淋巴结转移患者影响因素分析

317 Case Analysis of Risk Factors for Lymph Node Metastasis in Gastric Cancer

目的分析影响胃癌淋巴结转移的临床因素,提高对胃癌的认识及治疗水平。方法对有淋巴结转移的317例胃癌根治术患者的性别、年龄、肿瘤部位、大小、形态、分化程度、浸润深度等进行单因素及多因素分析,进行χ2检验。对P<0.01的各组变量赋值后进行多因素Logistic回归分析得出影响胃癌淋巴结转移的独立影响因素。结果性别、肿瘤大小、大体类型、组织学类型和浸润深度是淋巴结转移的影响因素(P<0.05);Logistic多因素回归分析显示:肿瘤大小、大体类型及浸润深度是淋巴结转移的独立影响因素。结论肿瘤大小、大体类型、浸润深度是胃癌淋巴结转移的独立影响因素,而浸润深度是最重要的影响因素。

Objective To analyze the clinical and pathological factors that affect the lymph node metastasis to study the relationship between biological behavior of gastric cancer and clinical factors so as to provide clues to the basis for clinical diagnosis and treatment. Method χ2test was used to investigate the factors for contributing to lymph node metastasis. Logistic multivariate regression analysis of the factors that had high significance was used to test the independent impact of the factors that contributed to lymph node metastasis. Results The gender,tumor size,gross type,histological type and depth of invasion were found to be the factors that had an impact（ P〈 0. 05）. Logistic multiple regression analysis suggested that the tumor size,gross type and the depth of invasion in lymph node were the independent impact of factor in lympth node metastasis. Conclusion The tumor size,gross type,depth of invasion all are indpedent factors in lymph node metastasis of gastric cancer,but the depth of invasion is the most important factor.