4214名健康体检者幽门螺杆菌检验结果分析

Prevalenceof Helicobacter pylori Infection Among the Healthy Asymptomatic Population

目的探讨大连地区体检人群幽门螺杆菌尿素酶抗体阳性率及分布特点。方法用胶体金法对2013年9月至2015年9月期间在大连市第三人民医院做体检的4214名健康体检者的幽门螺杆菌尿素酶抗体进行检测,以性别和年龄进行分组,对其检验结果进行统计学分析。结果 4214名健康体检者幽门螺杆菌总阳性率为21.76%（917/4214）;其中男性和女性健康体检者阳性率分别为23.98%（480/2002）、19.76%（437/2212）,男性和女性健康体检者幽门螺杆菌阳性率比较,差异有统计学意义（P〈0.05）;再将这些体检者分为〈45岁、45-59岁、60-74岁和75-89岁4个组,幽门螺杆菌阳性率在4个年龄组分别为19.13%（447/2337）、24.77%（357/1441）、26.09%（102/391）和24.44%（11/45）,组间幽门螺杆菌尿素酶抗体阳性率差异具有统计学意义（P〈0.05）。结论大连地区体检人群幽门螺杆菌尿素酶抗体阳性率分布与性别和年龄有关。

Objective To explore the prevalence of Helicobacter pylori（ H. pylori） infection and its distribution among the healthy asymptomatic population in Dalian. Methods 4214 of healthy asymptomatic population who had medical examination in 2013 and 2015 were included in this study. Helicobacter pylori infection was investigated by detecting Helicobacter pylori urease antibody. The resulting data was analyzed by SPSS 17. 0.Grouping was conducted based on gender and age. Results The Hp-positive incidence was 21. 76%,and the positive incidence in male and female was 23. 98% and 19. 94%, respectively. There was significant differences in the positive incidence between the male and female（ P〈0. 05）. The Hp-positive rate in the youth group（ age 〈44）,the middle age group（ age 45 to 59）,the young old age group（ age 60 to 74） and the old age group（ age 75 to 89） were 19. 13%,24. 77%,26. 09% and 24. 44% respectively. There were significant differences in the Hp-positive rates between different age people（ P〈0. 05）. Conclusion The distribution of the Helicobacter pylori infection in the healthy asymptomatic population in Dalian may be associated with sex and ages of people.