高通量测序技术在古DNA上的研究进展

Research Progress on Application of High Throughput Sequencing Technology in Study of Ancient DNA

古DNA研究经过30多年的蓬勃发展,尤其是在高通量测序技术广泛应用的历史背景下,在研究动植物的起源、驯化、进化以及系统发育重建等方面起到了重要作用。主要就近年来高通量测序技术在古DNA上的研究进展进行了综述,对古DNA研究存在的问题进行了归纳,并对其未来的发展进行了展望。

In the past 30 years, the investigation of ancient DNA has been vigorously developed. Under the background that highthroughput sequencing technology is widely employed, the ancient DNA plays an important role in clarifying the mechanism of origin, domestication, evolution and phylogenetic reconstruction of plants and animals. In this paper, the research progress on application of high throughput sequencing technology in investigation of ancient DNA was reviewed, the existing problems in study of ancient DNA were summarized, and the development of ancient DNA study in future was prospected.