摘要
热应激改变动物行为和生理机能,miRNAs作为22个核苷酸左右的非编码RNA,在转录后水平通过抑制靶基因参与机体的热应激调控。本文就miRNAs对热应激细胞生长、凋亡以及对热应激畜禽免疫、抗应激、器官损伤、生长性能和繁殖性能等方面所起作用及其机制进行综述。
Animal behavior and physiological function were changed under heat stress. miRNAs contained approximately 22 nucleotides in length regulated target gene of heat-stressed animal at the post-transcriptional level.This article mainly reviewed the effects of differential miRNAs expression on growth and apoptosis of heat stress cell,and the regulation of miRNAs on immunity,anti-stress responses,organic damage,performance and fertility,etc,and their mechanisms.
出处
《动物营养学报》
CAS
CSCD
北大核心
2016年第3期652-658,共7页
CHINESE JOURNAL OF ANIMAL NUTRITION
基金
国家自然科学基金(31372341)
十二五国家科技支撑计划(2012BAD12B02-05)
动物营养学国家重点实验室自主课题(2004DA125184G1103)
关键词
MIRNAS
热应激
畜禽
调控
miRNAs
heat stress
livestock and poultry
regulation
