摘要
迟发性运动障碍(Tardive dyskinesia,TD)是一组由多巴胺(DA)受体阻滞剂引起的迟发的医源性运动障碍,部分病例在运动障碍的基础上伴发感觉症状,如感觉异常、疼痛等。本文对TD的概念由来、病因学、发生率、危险因素、病理生理机制、临床表现、诊断、鉴别诊断、治疗及预防等作一综述。
Tardive dyskinesia（TD） is a group of delayed-onset iatrogenic movement disorders of various phenomenology caused by dopamine receptor-blocking agents. In some cases, the movement disorder may be accompanied by sensory phenomenon such as paresthesias and pain. This paper reviews the origin of concept, etiology,incidence, risk factors, pathological and physiological mechanisms, clinical manifestations, diagnosis, differential diagnosis, prevention and treatment of TD.
出处
《中国执业药师》
CAS
2016年第3期34-41,共8页
China Licensed Pharmacist
关键词
多巴胺受体阻滞剂
迟发性运动障碍
不良反应
Dopamine Receptor-blocking Agents
Tardive Dyskinesia
Adverse Reaction
