腹部手术患者代谢改变及加速康复策略

Metabolic response to surgical stress and therapeuticperspectives

外科手术患者围手术期发生一系列代谢改变，这是机体对术前准备和手术创伤的应激反应．而过度的代谢改变则可导致机体自身组织消耗．影响患者的临床结局。加速康复外科策略是根据机体代谢变化特征对围术期处理措施进行优化，可减少创伤和应激损害．促进机体快速康复。

Perioperative patients usually suffer from metabolic response. This metabolic state is usually the result of some blend of response to partial starvation and to injury or specific diseases. Metabolic response to starvation and acute injury is inbuih response to ensure maximal survival with a limited food intake. Yet, progressive loss of body tissue may have lethal consequences. Enhanced recovery after surgery is an optimized strategy of perioperative treatment based on variations of metabolic state. It can reduce damage and acute injury, as well as facilitating early recovery after major surgery.