超声瞬时弹性成像在眼内压估测中的价值

The value of ultrasound transient elastography in the estimation of intraocular pressure

目的探讨超声瞬时弹性成像在眼内压估测中的可行性及其价值。方法应用超声瞬时弹性成像技术对32例青光眼患者与28例正常人进行检查并获取眼球前壁的静态弹性图，使用Photoshop图像分析软件定量分析眼球前壁红、蓝、绿三颜色中蓝色色阶比值，比较正常人与青光眼患者眼球前壁静态弹性图蓝色色阶比值差异，再使用非接触式眼压计（NCT）测量眼内压，建立超声瞬时弹性成像眼球前壁蓝色色阶比值与NCT所测眼内压之间的相关关系。结果超声瞬时弹性成像测量的正常人眼球前壁蓝色色阶比值为0．33±0．02，青光眼患者眼球前壁蓝色色阶比值为0．37±0．03，二者差异有统计学意义（P〈0．01）；青光眼患者眼球前壁蓝色色阶比值与NCT所测眼内压呈线性正相关（r=0．424，P〈0．05）。结论超声瞬时弹性成像可用于正常人与青光眼患者眼内压的估测，所测眼球前壁蓝色色阶比值与NCT所测眼内压呈线性正相关。

Objective To explore the feasibility and the value of ultrasound transient elastography in the estimation of intraocular pressure. Methods Thirty-two cases of glancomatous patientsr and twenty- eight healthy subjectsr eyeball were examined by using ultrasound transient elastography, meanwhile using Photoshop image analysis software to quantitative analysis of blue gradation ratio of the front wall tissue of eyeball, then intraocular pressure were examined by NCT. The difference of quantitative data of blue gradation ratio of the front wall tissue of eyeball between glancomatous patients and healthy subjects were compared. The relationship of quantitative value of blue gradation ratio and intraocular pressure were established. Results The blue gradation ratio of the front wall tissue of eyeball in glancomatous patients were 0.37 ± 0.03, while in healthy subjects were 0.33 ± 0.02, there was a significant difference between glancomatous patients and healthy subjects （ P 〈 0.01 ）, and there was a linear relation between blue gradation ratio and intraocular pressure （ r = 0. 424, P〈0.05）. Conclusions The ultrasound transient elastography can be used in estimation of intra-ocular pressure in glancomatous patients, and there is a linear relation in quantitative data between blue gradation ratio and intraocular pressure.