摘要
目的明确阑尾开口炎（AOI）与溃疡性结肠炎（UC）同时存在时，两者内镜下炎症严重程度的关系。方法回顾性收集诊断为UC患者的病例资料，对伴随AOI的病例进行镜下UC和AOI炎症严重程度的线性趋势分析。结果UC的总病例数991例，检出率为2．3％（991／42928）。其中45例由于患者原因未行阑尾开口观察，其余946例UC病例中伴随AOI的例数为260例，阳性率为27．5％。不同炎症程度的UC中，AOI阳性率差异有统计学意义（χ2=27．39，P〈0．05），进一步两两比较显示，中度和重度UC的AOI阳性率差异无统计学意义[30．2％（109／361）比29．8％（147／493）,χ2=0．014，P〉0．0125]，但均明显高于轻度UC[4．3％（4／92），P〈0．0125]。在两者炎症严重程度是否相关的分析中，回归系数=0．32,χ2回归=29．48，差异有统计学意义（P〈0．05）,χ2偏=31．66，差异有统计学意义（P〈0．05），显示出两者成正相关但并非简单的线性关系。结论AOI是部分UC病例活动时的一个标志，内镜下其炎症严重程度可以反映UC炎症严重程度，这可能对部分UC病例的治疗后停药及其复发具有重要的指导意义。
Objective To evaluate the correlation of inflammatory severity between appendiceal ori- fice inflammation（AOI） and ulcerative colitis（UC）. Methods A retrospective analysis of the patients who were diagnosed as UC was conducted to investigate the correlation of the severity of inflammation between AOI and UC by linear trend test. Results The detective rate of UC during the above period was 2.3% （991/42 928）, with the patient number of 991.Appendiceal orifice observation did not perform in 45 cases due to patients reasons. In 946 patients, 260 cases were diagnosed as having AOI, which accounted for 27.5% of the total cases examined.AOI positive rates were significantly different between groups based on endoscopic severity standard（χ2= 27.39, P〈0. 05 ）, which was similar in moderate and severe group[ 30. 2% （109/361） VS 29. 8%（147/493） ,P〉0. 0125], both significantly higher than that in mild group [ 4. 3% （4/92） ,P〈 0. 0125 ]. In linear regression analysis, regression coefficient was 0. 32, χ2return = 29.48 （P〈0. 05 ）and χ2partial ： 31.66（ P〈0. 05）, which proved a positive correlation between the two drawn existed but not a simple linear relationship. Conclusion AOI is a sign in some active UC patients. Its severity of inflammation can reflect the degree of inflammation in UC, which may offer a terminal point when treating a slice of UC individuals and giving a signal of its relapse.
出处
《中华消化内镜杂志》
北大核心
2016年第3期155-159,共5页
Chinese Journal of Digestive Endoscopy
